With XenMobile 8.6 we added the option to enable multiple Netscaler Gateways. When companies want to provide additional security  to a specific set of application, we can now configure those application to connect to a higher secured Netscaler Gateway… see how to configure this…

AppController 2.9 provides the option to add additional Netscaler Gateways, allowing additional security to be enforced when using specific applications.

Second you can modify the MDX Application policy setting to use the defined Netscaler Gateway. when a tier 2 application is launched  the user session will be moved to that NS Gateway enforcing the Authentication  method and security defined for that level of security.

See video of the process